Concor is a medicinal product that is widely used in cardiological practice and is one of the most important basic medicines in medicine. Despite this, the remedy has a lot of contraindications and side effects, which it is better to inquire before treatment.
Composition and pharmacological action of Concor
The drug Concor represents a medicine in the form of tablets, covered with a film membrane. The main active ingredient is bisoprolol hemifumarate. Auxiliary components are such substances as calcium hydrophosphate, starch, crospovidone, microcrystalline cellulose, magnesium stearate.
Concor is well absorbed in the gastrointestinal tract, which is not influenced by eating. The drug is largely derived through the liver and kidneys. The maximum concentration of the main substance in the body is noted after 2-3 hours after administration, the therapeutic effect has a duration of about 24 hours.
Main pharmacological properties of the drug:
- Hypotensive. Reduction of blood pressure (due to a decrease in the activity of the renin-angiotensin system).
- Antianginal. Coping and preventing angina attacks (by lowering the oxygen norm for the heart muscle as a result of reducing the heart rate and reducing contractility, as well as prolonging the period of heart relaxation and improving perfusion ("pouring" blood) of the heart muscle).
- Antiarrhythmic. Elimination of cardiac rhythm disturbances (due to sympathomimetic activity, decrease in the rate of spontaneous excitation of the sinus node and other pacemakers).
Indications for the use of the drug Concor
Concor Medication is recommended for use in the following main cases:
- arterial hypertension;
- ischemic heart disease ( stable angina );
- extrasystole - ventricular and supraventricular;
- increased heart rhythm sinus node;
- arrhythmias with mitral valve prolapse or thyrotoxicosis;
- chronic heart failure (as part of complex therapy).
Compliance with dosage when using Concorc tablets
This medication should be taken once a day in the morning on an empty stomach, without chewing and washing down with a small amount of water. As a rule, the course of admission is quite long, with a gradual cancellation. Dosage, on average, is 5 mg per day, the maximum allowable amount of the drug per day is 20 mg. The decision on how long and in what dosage to take Concor is taken by the attending physician individually.
Side effects of Concor:
- excessive fatigue;
- dizziness;
- headache;
- nausea;
- stool disorders;
- vomiting;
- sensation of cold or numbness of limbs;
- reduction of tear;
- bronchospasm;
- hearing loss;
- itching;
- weakness in the muscles;
- sleep disorders, etc.
Contraindications to the use of Concor
The medicine can not be taken if there are:
- acute heart failure ;
- chronic heart failure in decompensated form;
- Raynaud's disease;
- cardiogenic shock;
- syndrome of weakness of the sinus node;
- bronchial asthma, chronic obstructive pulmonary disease of severe form;
- metabolic acidosis;
- late stages of peripheral circulatory failure;
- significant hypotension;
- increased sensitivity to the components of the drug, etc.
With care, the drug is prescribed during pregnancy and breastfeeding, expressed violations of liver function, diabetes, congenital heart disease, hyperthyroidism and some other pathological conditions.