Divigel is a pharmacological agent that is released in the form of a gel. The main active substance of this drug is estradiol.
Estradiol - a hormone of the estrogen group, which is produced in the female body in the ovaries. Estradiol affects the genitals, primarily the uterus, the mammary glands, the spongy substance of the bones, the skin and its appendages.
Sex hormones play an important role in the development of pregnancy and childbirth, with the exception is not and estradiol. Synthesis of estradiol at the end of pregnancy increases, which increases the excitability of the uterus, its sensitivity to oxytocin and other substances that cause uterine contractions.
The product Divigel contains a synthetic, identical to natural estradiol, its action is similar to the biological effect of endogenous hormone. The divigel is used for long-term and cyclic therapy in such cases:
- hormone replacement therapy with symptoms of estrogen deficiency;
- treatment of climacteric syndrome associated with physiological or artificial menopause in women who developed as a result of surgical intervention;
- prevention of osteoporosis in the absence of estrogen.
Divigel during pregnancy
The divigel is contraindicated for use during pregnancy and during lactation. He is appointed mainly in the period of preparation of the organism of the future mother for pregnancy, for escalating the endometrium of the uterus before fertilization. Therapy should be discontinued if there are contraindications to the use, such as:
- pregnancy;
- impairment of liver function;
- increased blood pressure ;
- attacks of migraine headache.
Divigel gel should be applied strictly according to the doctor's prescription and in individually selected doses.