Gonadotropin-releasing hormone agonists have a similar effect, and they are all equally effective in treating and reducing endometriotic foci, as well as in reducing symptoms of pelvic pain. And in terms of their effectiveness in treating pain syndromes, they are similar to progesterone.
Gonadotropin-releasing hormone antagonists are also used before surgery. This reduces the likelihood of developing ovarian endometriosis. However, not all specialists are equally convinced of the effectiveness and justification of the use of gonadotropin-releasing hormone in the preoperative period.
Gonadotropin-releasing hormone agonists (AHNRH) after surgery
The use of gonadotropin agonists in the postoperative period is due to its ability to reduce the risk of recurrence of endometriosis, and also to increase the period of development of a probable relapse. And then - these drugs are much more effective than conventional oral contraceptives in the process of treating pain in the pelvis after surgery.
Treatment of recurrences with gonadotropin
If relapse does occur, gonadotropin-releasing preparations may be administered repeatedly. However, you should select the dosage individually in such a way as to minimize the risk of complications such as osteoporosis.
In the second course of treatment, the risk of developing osteoporosis is somewhat reduced. In addition, this therapy also reduces the risk of complications from the bone tissue, so it can be used for two years.
Treatment of infertility AGGRG
Like other hormonal drugs, gonadotropin-releasing hormone agonists do not affect the likelihood of conception, so their use for this purpose is not justified. It is not recommended to use these drugs during pregnancy. And they are completely contraindicated in lactation, as their traces are found in breast milk.