Human chorionic gonadotropin is a hormone from the group of glycoproteins, which indicates the onset of pregnancy in the female body. It is the appearance in the urine of chorionic gonadotropin in pregnancy and explains the appearance of two strips on the test. Tracking the dynamics of the growth of the chorionic gonadotropin during pregnancy, it is possible to judge how pregnancy proceeds.
Chorionic gonadotropin in pregnancy is normal
Normally, in men and non-pregnant women, the β-hCG index ranges from 0-5 mU / ml. The level of chorionic gonadotropin begins to increase already in the first days after implantation of the embryo into the uterine cavity. It is produced by the tissues of the chorion and plays an important role in the normal course of pregnancy. Thus, human chorionic gonadotropin promotes the formation of the placenta, and also supports the normal operation of the yellow body (production of the hormone progesterone ). After the placenta is formed, it takes on the function of synthesizing the chorionic gonadotropin.
At the beginning of pregnancy, every two to three days, the indicator of h-hchch (human chorionic gonadotropin) is doubled. Starting from the 10-11th week of pregnancy, the rates of growth in the hCG significantly slow down, as the placenta is almost formed and begins to take on the function of producing hormones of pregnancy. So, in the first weeks of pregnancy, the rate of chorionic gonadotropin in the blood is in the range of 25-156 mU / ml. The gonadotropin level of chorionic 1000 mU / ml corresponds to the 3rd week of pregnancy. At 4-5 weeks this figure is 2560-82300 mU / ml, at 7-11 weeks after conception the level of chorionic gonadotropin in the blood reaches 20900-291000 mU / ml, and at 11-12 weeks it already decreases to 6140-103000 mU / ml.
Chorionic gonadotropin consists of two subunits - alpha and beta. The alpha subunit is identical in structure with that of thyroid-stimulating, luteinizing and follicle-stimulating hormones. The beta subunit is unique in its structure.
Gonadotropin chorionic - use
Gonadotropin human chorionic is used to treat infertility (stimulation of ovulation with in vitro fertilization, maintenance of the work of the yellow body). Chorionic gonadotropin for men is prescribed to stimulate spermatogenesis and the production of androgens (sometimes used in sports as doping).
The use of chorionic gonadotropin is indicated in the following pathologies:
- in women with insufficient luteal phase (to stimulate ovulation and maintain the vitality of the yellow body);
- in men with underdevelopment of the testicles, delayed puberty, hypogonadotropic hypogonadism.
The drug gonadotropin chorionic is contraindicated when:
- tumors of the sexual glands, as well as others caused by malfunctioning of the gonads;
- cryptorchidism caused by femoral hernia, trauma and surgery;
- individual intolerance of the chorionic gonadotropin.
How to prick a chorionic gonadotropin?
- The chorionic gonadotropin solution is available as an injection. Intramuscular injections of the gonadotropin dissolve well and are performed according to the doctor's prescriptions.
- Of the possible side effects can be identified increased blood viscosity and associated thromboembolic complications, as well as a syndrome of ovarian hyperstimulation. Boys can temporarily enlarge their mammary glands, they may develop swelling and acne.
We examined the role of chorionic gonadotropin in the body of a pregnant woman, and also got acquainted with the use of its synthetic analogues.