Osteoporosis is considered to be one of the most common diseases of the musculoskeletal system. And accordingly, over the methods of treatment, its specialists have to think about often enough. As practice has shown, bisphosphonates for the treatment of osteoporosis are suitable as well as possible. This group of medicines was known to medicine since the middle of the XIX century, but it was possible to obtain a wide circulation recently.
Medications-bisphosphonates
Certain compounds of bisphosphonates have long been used to provide protection against corrosion. They were often used in the oil and textile industries. Today bisphosphonates have managed to become the basis of drug therapy. They are salts of phosphorus, which contribute to the early formation of bone tissue and prevention of its destruction. That is, these drugs seem to have been specially created for the treatment of osteoporosis.
In addition to strengthening, bisphosphonates produce an anesthetic and antitumor effect. Thanks to this, bisphosphonate therapy is used for fractures and primary hyperparathyroidism. And the ability to work on malignant cells makes it possible to use drugs in oncology, accompanied by a weakening of bone strength.
What bisphosphonate drugs are used for osteoporosis?
All bisphosphonates can be conditionally divided into two large groups:
- containing in the composition of nitrogen;
- free from nitrogen.
The list of the most popular medicines looks like this:
- Bondronate is prescribed for both treatment and prevention of osteoporosis. Unlike some similar drugs, Bondronate can be taken even by women undergoing hormone therapy during menopause. In some cases, the medication is prescribed to patients with hypercalcemia .
- Bisphosphonate Ethidronate sodium is prescribed for osteoporosis and has proven itself in the treatment of diseases that have arisen against the background of oncology.
- Clodronic acid is used to selectively destroy macrophages. This drug perfectly anesthetizes.
- Medication Tiludronate is prescribed for patients with too soft bones to restore their density as quickly as possible.
- Risedronate prevents fractures of the spine and femoral neck - the most common injuries that occur in postmenopausal women.
Features of bisphosphonate treatment
It is important to understand that strengthening bones is not the fastest process. And although the bisphosphonates act fairly quickly, they have not been able to solve the problem for several days. So, starting the treatment, the patient needs to prepare himself for the fact that the course at best will last a year. Usually bisphosphonates take a few years. But the results of this treatment impress with their thoroughness.
These are very strong medicines. All preparations containing bisphosphonates do not dissolve very well in the body. Therefore,
- It is best to drink bisphosphonates in the morning on an empty stomach at least an hour and a half before meals.
- It is recommended to drink a tablet with plenty of water. Use any other liquid (tea, juice, milk) is very undesirable.
- To the tablet was easier to get to the destination, after taking it preferably for an hour or a half to sit or stand.
The most suitable preparation and its dosage should be selected by a specialist after a comprehensive preliminary examination.