Desloratadine and loratadine - differences

To quickly understand what desloratadine is, remember a popular drug like Erius . This is a fairly common remedy for treating allergies. Its active ingredient, desloratadine, is a metabolite of loratadine. This factor caused different effects of the two substances. Desloratadine and loratadine, the differences of which are presented below, effectively combat hypersensitivity to various irritants, relieve puffiness and exert an antiexudative action.

What is the difference between loratadine and desloratadine?

Both substances block histamine n1 receptors. They do not have cardiotoxic and hypnotic action, they are quickly eliminated from the body without delaying it.

However, desloratadine is a loratadine metabolite, that is, it is a product of processing. Thus, when taking loratadine, he, before starting his action, turns into desloratadine. Therefore, the latter starts much faster than the preparation of the previous generation, since it does not need to be converted to a final substance.

Which is better - desloratadine or loratadine?

The advantages of desloratadine include its high efficiency. It is 4-15 times more active than its predecessor. This allows quickly reach maximum concentration and reduce dosage in half.

It is worth noting that most drugs based on desloratadine are sold as a syrup, which makes it possible to treat children, starting with six months.

Considering desloratadine and loratadine and answering the question what is the difference, it is worth noting that when the latter is required, the normal functioning of the liver is required. After all, in the case of any pathology, conversion to desloratadine will become impossible.

The cost of drugs based on desloratadine is an order of magnitude higher than that of loratadine. The last medicine should be given preference if it is necessary to fight with single cases of allergy , in the absence of liver diseases.