Treatment of gout - drugs that excrete uric acid

Gout is a disease associated with a pathological change in the joints. The cause of gout is a high level of uric acid. For the disease characterized by acute pain attacks in the joints (most often in one of the big toes), redness and swelling of the skin in the affected area. If the disease is not treated, then on the bone erosion is formed. The question of how to remove uric acid from the body, and what drugs contribute to getting rid of excessive amounts of urate in the blood, is solved taking into account the etiology of the disease.

Review of drugs for the treatment of gout, excreting uric acid

With gout, a diet that helps reduce purines is recommended, but uric acid can not be removed with the help of proper nutrition. In this connection, when manifesting the symptoms of the disease, it is mandatory to contact a specialist. Based on laboratory tests of the patient's urine, the doctor prescribes appropriate therapy. For the treatment of gout, 2 types of medicines are used:

• drugs that excrete uric acid from the body;
• drugs that reduce the concentration of uric acid in the tissues of muscles and joints.

Next, we will consider in more detail the drugs that remove uric acid from the body.

Probenecid (Probenecid)

Probenecid is one of the most commonly used drugs for gout that excretes uric acid. The drug blocks the reabsorption of uric acid in the tubules of the kidneys, thereby enhancing its excretion. In the chronic course of the disease, the initial single dose is 250 mg with the administration twice a day. After a week, the dose is usually increased to 500 mg with a two-time intake per day. In case of insufficient effectiveness of drug therapy, the dosage can be increased, but it should be borne in mind that the maximum daily dose does not exceed 2 g. Probenecid belongs to long-acting preparations. In the absence of acute gouty attacks for 6 months, if in addition the concentration of urate is normal, the dose is gradually reduced to a minimum.

Blemaren

One effective remedy for treating gout is Blamaren. The drug normalizes metabolism, alkalizes the body, with uric acid stones gradually dissolving. A significant plus is that Blamaren does not interfere with the normal functioning of the kidneys and liver, because of which the medicine can be taken without risk to the health of pregnant and lactating women. The daily dose is 2 - 6 tablets. Duration of treatment - up to 6 months. Before taking effervescent tablets dissolve in a glass of liquid. It can be mineral water, fruit juice, compote or tea.

Allopurinol (Allopurinol)

Allopurinol - a drug that affects the synthesis of uric acid , reducing its concentration in the body fluids, including in the urine. The doctor determines the dosage of the medicine individually, taking into account the severity of the disease. The daily dose of Allopurinol can range from 100 mg to 900 mg. Multiplicity of admission - 2-4 times a day directly after eating. The drug can be used in the treatment of children, 10-20 mg per kilogram of the child's weight is prescribed per day. Allopurinol is contraindicated for use during pregnancy and lactation. In addition, the drug can not be taken with severe dysfunction of the thyroid gland, kidneys and liver. In case of a decrease in the function of the liver or kidneys, a reduction in the dosage of the drug should be provided.

We hope the material about what drugs are removed from the body uric acid, it will be useful if you have gout in the inactive stage. Remember that it is impossible to remove uric acid in the event that the signs of the disease are already obvious.