How is the formation of male sex cells?
Before to tell about what quantity of cells of a spermatogenesis in norm or rate can be present in spermogramme, let's briefly consider the process of maturing of a spermatozoon.
Thus, the formation of male sex cells in boys begins at about 12 years and lasts until old age, throughout the life of a man. At the same time, it is normal to assume that the duration of one cycle of spermatogenesis is about 75 days.
The formation of male sex cells begins directly inside the convoluted seminiferous tubules of the testicles. Each of their tubules is divided by a special septum into two halves. In one of them intermediate elements of spermatogenesis are located, and in the second - spermatogonia, which subsequently give rise to spermatozoa. Normally, one testicle contains more than a billion such cells.
Which cells are immature and how much should they contain in the spermogram?
As a rule, the presence of a large number of cells of spermatogenesis leads to the development of disorders in men. That is why this indicator is one of the main ones in evaluating the results of such a study.
Immature cells of spermatogenesis are also often called spermatogenic. These include:
- spermatogonia - stem cells, which are the basis for the formation of spermatocytes;
- spermatocytes 1 (remain in mitosis as a result of incomplete cell division) and 2 orders (enter 1 prophase meiosis, complete the first division, forming as a result 2 spermatocytes each);
- spermatids (have haploid set of chromosomes and after structural changes are transformed into spermatozoa).
It is worth noting that single cells of spermatogenesis are present in any spermogram. So, in norm their concentration should not exceed 5 million / ml of sperm. However, sometimes, in the presence of violation, the excess of this indicator is noted 10 times. Recent studies have shown that this indicator is not of great diagnostic value.
Much more important in determining the cause of the disorder is the content of cells in the sperm cell, such as leukocytes, or rather, their form, such as neutrophils. The total number of them should not exceed 1 million / ml. Otherwise, there is a development of such a violation as leukospermia, which adversely affects the ability of male germ cells to fertilize.
What if the spermiogram revealed an increased number of spermatogenesis cells?
As already mentioned above, even in normal spermatogenesis cells can not be absent in the sample of the ejaculate. However, if their total number exceeds 5 million / ml, then in this case they speak of pathology.
This kind of violation is the failure of the process of formation of spermatozoa.
In such situations, a man is prescribed treatment, which is aimed at the normalization of spermatogenesis, which, first of all, is achieved by the appointment of hormonal drugs.
Thus, it can be said that the presence in the spermogram of immature cells of spermatogenesis is not a violation if their concentration does not exceed the established norm.