In the body of a healthy person, the processes of formation of thrombi (blood clots) and their dissolution are constantly occurring. The emergence of tissue or epidermal damage leads to the activation of many processes aimed at eliminating the defect. Thrombi are formed from cellular substances released from destroyed tissues, and from noncellular, synthesized in the liver. Therefore, often bad coagulability indicates the presence of problems with this body. Let's consider other basic factors of development of this disease.
Causes of pathology
Poor blood clotting can occur for the following reasons:
- hereditary trabeculation (platelet defects);
- liver disease (in particular, hepatitis), which are the cause of a decrease in the number of factors involved in blood coagulation;
- excessive blood loss, which, despite the infusion, reduces the amount of clotting substances;
- a decrease in the number of platelets due to thrombocytopenia, deficiency of factors X, V, II and VII;
- capillary-hematoma type of hemorrhage is observed in DIC syndrome, Villebrant disease and XIII factor deficiency;
- the presence of hypofrinogenemia is accompanied by capillary hemorrhage, in which hematomas and rashes are present on the skin;
- poor blood coagulability often results from a disease such as DIC syndrome, which is caused by shock, early separation of the placenta and sepsis;
- when the walls of the vessels are damaged by immune vasculitis , intestinal hemorrhages, skin rashes and nephritis occur.
Answering the question why there is a bad coagulability of blood, we can not avoid the hereditary diseases (deficiency of VII factor and hemophilia). Also, the cause of bleeding is an overdose of anticoagulants, in which blood outflows into muscles, intestines, under the skin, joints are observed.
Poor blood clotting - symptoms
The signs of this disease manifest themselves as follows:
- excessive bleeding gums and wounds;
- sharp bruises that can be accompanied by bleeding from the nose or from other places;
- difficulty in trying to stop the blood.
To the signs of poor blood coagulation should be attributed the emergence of small hematomas. If this phenomenon is observed in childhood, then the cause may be Villebrand disease.
Treatment of the disease
Increase the number of clotting factors can be achieved by the use of certain drugs. The process of treatment itself is quite long. In the case of congenital disease, the patient must take medicines throughout life. If the deterioration of coagulation developed due to acute pathologies, the patient is prescribed a course of therapy with a long-term rehabilitation.
Means to combat poor blood coagulability and its treatment are chosen, based on the causes of the disease:
- When bleeding, the coagulants obtained from the donor plasma are used. The hemostatic tube is used topically for stopping
bleeding of the smallest sosudikov. The fight against hypofrinogenemia occurs by intravenous injection of fibrinogen. - Aminomethylbenzoic and aminocaproic acid and Contrikal possess an excellent hemostatic property. These drugs are able to prevent the dissolution of blood clots.
- The use of such a coagulant, like vitamin K, helps restore the work of clotting factors occurring in the liver. This remedy is also used for an overdose of anticoagulants and hypoprothrombinemia.
- Treatment of poor blood clotting caused by Villenbrand disease and hemophilia includes intravenous injection of cryoprecipitate and antihemophilic plasma by jet.