Antimycotics are an extensive group of medicines that can effectively combat various types of fungi that affect the human body. Some of them, as a rule, are the earliest medicines, have a narrow focus and are active only in relation to some forms of pathogenic microorganisms. More modern antifungal preparations of a wide spectrum of action in tablets are more in demand. They provide suppression of growth and reproduction of almost all types of pathogens, which is very important when it is impossible to conduct accurate laboratory studies.
Are human antifungal agents safe for a wide range of activities?
The type of pharmacological agents considered is considered quite toxic. Systemic antimycotics, like antibacterial drugs, have a negative effect on the liver and digestive system, often cause unpleasant side effects in the form of dyspeptic disorders, among which:
- pain in the epigastric zone;
- constipation or diarrhea;
- heartburn;
- loss of appetite;
- bloating of the intestine;
- increased gassing;
- eructation;
- heaviness in the right and left hypochondrium;
- unpleasant (sour, bitter) taste in the mouth;
- burning in the esophagus;
- spasms of the intestine.
Of course, it is difficult to call antifungal drugs very dangerous to human health, but when using them, it is still important to be cautious. Specialists recommend strictly adhere to the prescribed dosages and developed treatment regimen, take medication at the same time intervals and do not interrupt the prescribed course without the doctor's permission. Otherwise, the risk of recurrence of mycosis or its transition to a chronic form is high.
Types of broad-spectrum antifungal drugs in tablets
Antimycotics of various directions are classified into 3 groups:
- Polyene. These drugs have the widest spectrum of activity, but they are resistant to fungi-dermatomycetes and pseudoallieseries. Therefore, the main field of application of polyenes is candidiasis of the gastrointestinal tract, skin and mucous membranes.
- Azoles. These antifungal drugs in tablets are effective for the treatment of mycosis of the nails of the hands and feet, the skin, including the scalp, mucous membranes. They also help from some types of lichen.
- Allylamines. Antimycotics, which are usually prescribed for various dermatomycosis and lichen caused by dimorphic, moldy, higher and other fungi.
Other groups of drugs presented have a narrow focus, and therefore are not considered.
The best broad-spectrum antifungal agents
Among the many modern antimycotics, one should pay attention to such names:
1. Polyenes:
- Levorin;
- Ampholip;
- Nystatin;
- Ambiz;
- Natamycin;
- Amphotericin B;
- Pimafucin;
- Amfocil;
- Fungizon;
- Amphoglucamine.
2. Azoles:
- Canditral;
- Diflucan ;
- Itraconazole;
- Mycomomax;
- Irunin;
- Fluconazole;
- Mycosyst;
- Oronazole;
- Itrazole;
- Mycoflucan;
- Orungal;
- Ketoconazole;
- Flucostat;
- Rumikoz;
- Orunite;
- Nizoral;
- Vero-Fluconazole;
- Medoflucon;
- Diflason;
- Mycosorrhal;
- Fungavis.
3. Allylamines:
- Terbisyl;
- Bramisil;
- Terbinafine;
- Extern;
- Terbinox;
- Lamisyl.
It is important to note that the use of only oral antifungal drugs is ineffective. For a full-fledged treatment of any mycoses, complex therapy is required, involving the administration of systemic medicines and simultaneous application of local antimycotic agents in the form of creams , ointments or solutions.