Anticonvulsant drug Diphenin has analogues, which in their composition and their effectiveness are not inferior to this drug.
Features of the drug Diphenin and its analogues
The drug is a hydantoin derivative. It has the following effect:
- anticonvulsant ;
- analgesic;
- antiarrhythmic;
- miorelascing.
During the intake of Diphenin tablets, a slow absorption occurs. Phenitonin, which is part of the drug, penetrates into the brain fluid, saliva, stomach, and intestinal juice. It can also be excreted through breast milk, which makes it dangerous for the baby and banned during lactation. In this case, the drug is excreted through the kidneys in the form of metabolites, and then - through the intestine.
Like any drug, Diphenin has a number of contraindications:
- Morgagni-Adams-Stokes syndrome;
- sinoauric blockade;
- sinus bradycardia;
- blockade of 1-3 degrees;
- period of pregnancy and lactation;
- alcoholism;
- diabetes;
- liver failure;
- fever;
- carchemy;
- sensitivity to individual components of the drug.
It should be said that the drug and similar drugs have special instructions during the period of application. For example:
- It is important to constantly check the concentration of phosphorus and calcium in the blood serum.
- People with epilepsy should gradually discontinue the drug or switch to another anticonvulsant without a hydantoin derivative, as abrupt reversal of it can lead to adverse effects.
- Do not combine diphenin with acetazolamide, because there may be a risk of developing rickets or osteomalacia.
- Combining such a drug with Gabalentin can cause the development of toxic effects.
- Tablets containing phenytoin, inhibit the psychophysical reaction, so people who constantly need to be careful and respond quickly to what is happening, this medication is contraindicated.
How to replace Diphenin?
Those who are interested in the question, what can replace Difenin, you should see the list below. It lists medications that are similar to the indications for use and pharmacological action. The following medicines are analogues:
- Alepcin;
- Gidantal;
- Gmidantoinal;
- Digidantoin;
- Dilantin sodium;
- Difantoyin;
- Diphedan;
- Zentropil;
- Sodanton;
- Solantil;
- Solantoin;
- Fengidone;
- Phenytoin;
- Epanutine;
- Eptoin.