The use of the lidase drug in gynecology is caused directly by the action of the main substance of the drug - hyaluronidase. Hyaluronidase is an enzyme that breaks down the component of the interstitial substance of the connective tissue - hyaluronic acid. Therefore, the main pharmacological effect of the drug is to increase tissue and vascular permeability, facilitate the movement of fluids in the interstitial spaces, soften the scars. Because of this action, lidase in gynecology is very often prescribed in the treatment of adhesive processes in the fallopian tubes .
Adhesions are rumen-like formations of connective tissue, on this basis, one of the ways of treatment is the administration of lidase. Adhesive processes can cause infertility in women. To date, there are two ways to treat adhesions - surgical and conservative. Naturally, the most effective and rapid is the surgical method: with strongly pronounced adhesions, their dissection occurs. However, this method is not always effective in relapsing inflammatory processes. Therefore, a complex conservative treatment is often used, which implies an effect on the already formed adhesions and the prevention of inflammatory processes, because of which spikes often arise. One of the methods of conservative treatment is the use of enzyme preparations, and, as an option, lidases.
Lidase is a preparation of animal origin, isolated from the testes of cattle. Since it is more physiological in origin, then with prolonged and massive drug treatment, its side effect will be lower in comparison with chemotherapy drugs.
The use of lidase in gynecology
The most frequent method of administration of the drug is electrophoresis with lidase - a physiotherapy procedure in gynecology, in which the substance is delivered directly to the affected organs. Electrophoresis is a complex action of direct current and drugs administered with it. This is a unique combination of a gentle method of influence and level of effectiveness: the drug is administered in minimal doses, without using the digestive system, bypassing the blood and lymph, directly to the affected area.
Lydase in gynecology is also often used in the form of candles, which are used to treat interstitial cystitis and tubal peritoneal infertility. Lidase in the form of injections in gynecology is used less often, and mostly directly with surgical intervention. When administered subcutaneously, the effect of the drug is 48 hours.
The use of lidase in gynecology is most effective at the initial stages of the disease - after the inflammatory processes of the small pelvis, adnexitis, salpingitis, endometriosis , surgical intervention. However, in the chronic course of obstruction of the fallopian tubes due to previously transferred diseases, treatment with lidase is expedient in combination with therapeutic exercise and diet.
Often when treating gynecological diseases, tampons with lidase, Vishnevsky ointment, dimexide are used. In this case, lidase improves the absorption of drugs.
It should be noted that acute infectious and inflammatory processes are a contraindication to the use of lidase in gynecology, as well as hypersensitivity to the drug, concomitant use of estrogens, recent hemorrhages, breast-feeding, pregnancy. When prescribing this medication, it is recommended to carry out a test for sensitivity to hyaluronidase: 0.02 ml of hyaluronidase is intradermally injected and the test is evaluated.
And most importantly - in any case, in any disease progression, a qualified consultation of a specialist doctor is necessary, and the use of lidase in gynecology only after its appointment.