In severe hepatological diseases, accompanied by a violation of production and outflow of bile, acid-base balance, intoxication of the body and destruction of hepatocytes, treatment with medicinal products is required. Depending on the mechanism of action and the main ingredients, they are divided into several groups - drugs based on bile acids, organic products (plant and animal origin), derivatives of amino acids and phospholipids. Also there are biologically active additives (BAA) and homeopathic medicines.
List of drugs with bile acids for liver treatment
This type of medicine refers to the most potent means for cleansing bile from cholesterol, detoxification of the liver and restoration of its functions. Such drugs are produced on the basis of ursodeoxycholic acid (UDCA) and are prescribed for serious hepatological pathologies - cirrhosis , acute hepatitis, severe toxic and alcoholic liver damage.
List of funds based on UDCA:
- Ursosan;
- Ursofalk;
- Livedoksa;
- Ursuliv;
- Urdoks;
- Exxhol;
- Ursodez.
It is important to note that preparations with bile acids have a number of contraindications and additionally produce a pronounced immunomodulating effect. Therefore, their independent use is unacceptable, even dangerous. Therapy should be coordinated with the hepatologist.
Best drugs of organic origin for liver treatment
This kind of medicines is divided into 2 subgroups:
1. Means based on medicinal herbs (milk thistle, artichoke):
- Karsil ;
- Legalon;
- Gepabene;
- Sylimar;
- pills and milk thistle.
2. Medicines of animal origin:
- Hepatosan;
- Sirepard;
- Progepar.
The latter subgroup is a drug for the treatment of fatty liver hepatosis, cirrhosis and severe hepatitis. These medicines are not used as a preventive measure and are dispensed solely on the prescription of a doctor. They produce a pronounced complex effect, consisting of hepatoprotective, antioxidant and detoxification action, stimulate the regeneration of hepatocytes and the restoration of parenchymal tissue.
New drugs based on amino acids for liver treatment
The presented type of drugs is produced on the basis of ademetionine and aspartate aspartate. Medicines promote the cleavage of lipid compounds and their removal from the liver, detoxification of the body, improve cholestasis.
List of amino acid preparations:
- Heptor;
- Berlition;
- Hepa-Mertz;
- Tioctacid;
- Glutargin;
- Espa-Lipon;
- Heptral.
At clinical researches of the specified means it has been established, that their oral reception does not make practically any positive effect. High efficacy can be achieved solely by intravenous drip medication administration.
Effective treatment of the liver with phospholipid drugs
Phospholipids are the most popular and popular medicines in hepatology practice, therefore their choice is rather wide:
- Essley Forte;
- Gepagard Active;
- Essentiale N and Essentiale Forte H;
- Phosphontsiale;
- Resalute Pro;
- Phosphogliv;
- Livolin Forte;
- Esledin.
Despite the large list of expected positive results of treatment according to the instruction, the effectiveness of the listed facilities is being questioned. In the course of medical research, no positive effects of these drugs on liver function were revealed. Moreover, with viral hepatitis, they provoke stagnation of bile, which contributes to the activation of inflammatory processes.