The preparation Polyoxidonium is one of the effective immunomodulators that help individual organs and the body as a whole to resist a variety of infections. It is often prescribed as part of complex therapy of serious diseases, for prophylactic purposes, for restoration of immunity after the transferred pathologies.
The drug in question has several forms of release: tablets (for oral and sublingual administration), lyophilizate for the preparation of a solution (for intranasal and parenteral use) suppositories (for vaginal and rectal administration). We will become acquainted in more detail with the features of Polyoxidonium preparation for parenteral administration, i.e. for injections, we learn what are his indications and contraindications.
Composition and therapeutic effect of injections Polyoxidonium
The active ingredient of Polyoxidonium is azoximer bromide, auxiliary substances: mannitol, povidone, beta-carotene. The lyophilizate is released in ampoules or glass bottles complete with a solvent placed in ampoules, which can be both water for injection and sodium chloride solution isotonic.
The drug is characterized by excellent bioavailability, quickly penetrates into the bloodstream and is distributed to all tissues and organs. Thanks to the action of the main component of the drug, the body's resistance to bacterial, viral and fungal infections increases. This is achieved by stimulating the natural antibody formation to pathogens, activating the processes of production of protective cells.
Along with this, the detergent has detoxifying and antioxidant properties due to the structure of Polyoxidonium. Due to this, it increases the resistance of cellular membranes to the toxic effects of drugs and chemicals, reduces their toxicity.
Injections for immunity Polyoxidonium provide an opportunity to increase the efficiency and reduce the duration of the treatment course, reduce the dosage of antibiotics, glucocorticosteroids, and also extend the period of remission. As studies show, this drug is well tolerated, does not have allergenic, carcinogenic, mutagenic properties.
Indications for the use of injections Polyoxidonium
Polyoxidonium injections can be done when the chances of a cold, flu and other acute respiratory diseases are high for the purpose of prevention. Also for preventive purposes, it is advisable to use the product after the operations and injuries that have been carried out. For medicinal purposes, the drug may be administered as part of a complex therapy with:
- tuberculosis;
- herpesvirus infection;
- urogenital bacterial infections;
- acute and chronic allergic diseases ( pollinosis , atopic dermatitis, bronchial asthma, etc.), complicated by infectious processes;
- Rheumatoid arthritis, which for a long time was treated with immunosuppressants ;
- oncological diseases during or the field of chemotherapy and radiation therapy.
How to plant Polyoxidonium injections?
For intramuscular injections, one ampoule with 6 mg of the drug should be diluted with 1.5 - 2 ml of physiological saline or prepared water. For intravenous injection of the lyophilizate ampoule, 6 mg is diluted with 2 ml of physiological solution, hemodeza-H, rheopolyglucin or dextrose solution (5%), and then the solution is transferred to a 200-400 ml dropper. It is worth considering that
Contraindications to injections Polyoxidonium:
- individual intolerance to the components of the drug;
- pregnancy;
- lactation.
With caution, the drug is used in acute kidney failure, lactose intolerance, glucose-galactose malabsorption syndrome, lack of lactase.