Immunoglobulin during pregnancy

Pregnancy is always a burden on the woman's body, even if it runs without complications. One of the conditions of a normal course of pregnancy is a decrease in immunity. This is due not only to the increased requirements for the work of all systems, but also to the fact that a decrease in immunity contributes to the fact that the fetus, which is inherently an alien object, will not be torn away. There is a vicious circle on the one hand, a decrease in immunity is necessary, on the other hand low immunity can cause infectious and other diseases, as well as cause a deterioration in the general condition of the pregnant woman, which does not contribute to the bearing of the child.

In case of problems with pregnancy, a normal human immunoglobulin can be administered to a woman. The active substance of this drug is released from human plasma, purified and concentrated. Has immunomodulating and immunostimulating properties. The introduction of immunoglobulin during pregnancy helps to resist various kinds of infectious agents, replenishes an insufficient number of JgG antibodies. This is especially important for women with an initial immunodeficiency. However, in any case, human immunoglobulin during pregnancy is prescribed according to strict indications, in cases when it is really necessary.

If there is a rhesus-conflict between the mother and the fetus (which happens when a woman is Rh-negative, and the conceived child is Rh-positive), an anti-D-immunoglobulin (antiresusive immunoglobulin) is prescribed.

If necessary, the human immunoglobulin is administered from the first pregnancy, and the antiresusive immunoglobulin is aimed at preventing the conflict in the second pregnancy and subsequent. At the first - the Rh-conflict does not develop because the mother has not yet developed a large amount of antibodies to the antigen. Mom, antibodies produced by her, do not do harm, but their impact on the child can be fatal. He threatens to be born with serious mental disabilities, brain damage, with severe hemolytic jaundice. Therefore, anti-D-immunoglobulin should be administered within 72 hours after the first birth. If the first pregnancy was preceded by abortions, miscarriages at any time, amniocentesis or abdominal injuries, in which it was possible to get fetal blood into the bloodstream of the mother, and also if the blood was transfused with Rh-positive blood, then the introduction of an antiresusive immunoglobulin is also advisable in the first pregnancy. It is best to be under the supervision of a doctor and regularly take a blood test for the presence of antibodies, and in case of threatening Rh-conflict, take the necessary measures. Sometimes the risk of rhesus conflict also occurs at the 28th week of pregnancy, which will be seen during the survey. In this case, the immunoglobulin is added.

Immunoglobin is administered in the form of intramuscular injections or intravenously drip. Dosage is calculated by the doctor strictly individually. After the introduction (especially the first), side effects can be observed:

In addition, the effect of this drug on the body of the pregnant woman and the fetus has not been properly studied. Therefore, the introduction of immunoglobulin during pregnancy is necessary only when the risk of the disease is higher than the risk of drug administration.

Herpes and pregnancy

The herpes virus has in its body the vast majority of the population. In pregnancy, favorable conditions for exacerbation of herpetic infection are created. It is very dangerous if a future mother becomes infected with herpes during pregnancy, since the virus can penetrate the placenta and cause developmental defects in the child or provoke a miscarriage. Infection in the third trimester of pregnancy is fraught with stillbirth or total defeat in the child of the brain. Less dangerous is the situation when a woman already had herpes before pregnancy, as the antibodies developed in previous infections and protecting the fetus circulate in her blood. For the treatment of herpes in pregnancy use approved antiviral drugs and ointments. If immune deficiency is diagnosed, then herpes during pregnancy is treated with immunoglobulin.