In view of the increase in infections caused by bacteria, the use of antimicrobial agents in the modern world is indispensable. In this case, as doctors insist, antibiotic therapy should be strictly justified. Let's consider, what rationality of purpose or appointment of tablets Nolitsin, indications to application of this preparation, features of reception is.
Nolitsin - composition
This medication is made in the form of tablets for internal reception, covered with a film membrane. In the preparation Nolitsin, the active substance is norfloxacin, which is a synthetic compound containing fluorine atoms. Each tablet contains 400 mg of the active ingredient. The medicine is packed in blisters and cardboard packages.
In addition, the tablets contain in their composition additional components: povidone, sodium carboxymethyl starch, microcrystalline cellulose, pyrogenic silicon dioxide, magnesium stearate, water prepared. The film-shell is made on the basis of hypromellose, titanium dioxide, talc, propylene glycol, with the addition of dyes.
Is Nolycin an antibiotic or not?
Patients who are prescribed to treat the drug in question, often worried about whether Nolitsin is an antibiotic. Initially, since the discovery of the first antibiotics, which were obtained from mold and bacteria, this term denoted medicines of organic origin. When scientists learned how to obtain highly effective drugs that have a harmful effect on the bacterial flora, from synthetic compounds, such medicines have been called antibacterial chemotherapeutics.
Now the above concepts are somewhat vague, and the term "antibiotic" is used to refer to both natural, synthetic, and semi-synthetic drugs. Therefore, Nolycin, the indications for use of which are discussed below, can be reliably attributed to the list of modern antibiotics. According to the classification, he belongs to the group of second generation fluoroquinolones .
Nolicin - what is it used for?
The described preparation acts bactericidal against a wide range of microorganisms, including:
- staphylococci;
- E. coli;
- enterobacteria;
- citrobacter;
- salmonella;
- cholera vibrio;
- Klebsiella ;
- shigella;
- Proteus;
- chlamydia;
- legionella;
- hafnii and others.
Nolitsin tablets have a depressing effect on the pathogenic microflora due to the suppression of the production of important enzymes in bacterial cells, the disruption of the synthesis of DNA and proteins. Quickly absorbed from the gastrointestinal tract, the drug is well distributed to the tissues of the body through the blood. Its maximum concentrations are found in the digestive and urogenital organs.
Nolitsin - indications for use:
- bacterial infections of the urinary system (acute, chronic, complicated): cystitis, pyelitis, urethritis, pyelonephritis, etc .;
- infectious diseases of internal genital organs caused by sensitive pathogens: endometritis, cervicitis, etc .;
- gonorrhea (without complications);
- gastroenteritis of bacterial genesis;
- typhoid fever;
- "Traveler's diarrhea";
- sepsis in patients with neutropenia (as a preventive measure);
- diseases of the respiratory tract (pneumonia, bronchitis, etc.) - rarely.
Nolitsin with cystitis
Cystitis is a common disease of the urinary system. Pathology affects the walls of the bladder, causing their inflammation. Often, the perpetrators are bacteria that penetrate the urethra and are attached to the mucous membrane of the organ. Also the pathogenic microflora is able to penetrate the bladder from the kidneys, neighboring organs of the small pelvis. Recognize cystitis simply by such characteristic clinical manifestations: frequent painful urination with a feeling of incomplete emptying, blood in the urine, an increase in body temperature.
To treat this disease, it is rational to prescribe antibiotic agents, including the use of Nolicin (400) tablets in this case, in view of the popularity of the potential causative agents of infection. If you start an adequate antibiotic therapy immediately after the diagnosis of the disease, its course is not complicated, and recovery occurs in the shortest possible time. To completely eliminate the infectious and inflammatory process, there is often enough three-day therapy, sometimes combined with taking antispasmodics to relax the muscles of the bladder.
Nolitsin with pyelonephritis
The diagnosis of "pyelonephritis" is another pathology not rare for women, in which renal pelvis, calyx and kidney parenchyma are involved in the inflammatory process. Bacterial microflora penetrates in many cases from other inflammatory foci in the body by hematogenous way. The disease, passing in an acute form, is characterized by pain in the lumbar zone on the side of the lesion, a feverish condition, a change in the color of urine,
With pyelonephritis, you can take Nolitsin, which, along with other fluoroquinolones, acts in this pathology as a drug of choice. Moreover, the drug is suitable for both arresting an acute infection and for a chronic process. As indicated by the indications for use, Nolicin for the treatment of this lesion is often prescribed by the course from 10 days to 6 months, depending on various factors.
Nolycin with ureaplasma
Ureaplasmosis is an inflammatory lesion of the genitourinary system, provoked by microorganisms ureaplasmas, which belong to the list of conditionally pathogenic representatives of the natural microflora of most women. Their activation and increase in the number can be observed with a decrease in immune defense, and it is still possible to infect the infection by sex. Affected by pathogens female genital organs - uterus, appendages, vagina.
Unambiguously, we can say, and this is evidenced by indications for use: Nolicin tablets with ureaplasmosis is not always appropriate. This is because most strains of the pathogen are not sensitive to this antibiotic and can not be eliminated when it is taken. At the same time, the drug shows moderate activity to some subspecies of ureaplasma. Therefore, prescribe this medicine should be after bacteriological analysis.
Nolycin from thrush
Indications for use of the drug Nolitsin do not provide for the use of it for the treatment of candidiasis, tk. Fungal microflora is insensitive to the action of its active component. On the contrary, with the treatment of bacterial infections, especially those requiring a long-term course, often with a balance of microflora in the body, thrush develops in the body. Therefore, using the medicine Nolitsin, will not prevent the parallel preventive use of funds that suppress the candida.
Nolitsin with inflammation of the appendages
Appendages in women are called ovaries, in which ovules mature and sex hormones are produced, and fallopian tubes, through which the eggs move into the uterine cavity. Normally, these organs are sterile, but under the influence of various factors, bacterial inflammation can develop there, often in a latent form. Meanwhile, such a defeat often causes infertility. Therefore, it is very important to identify the infection in time and to eliminate it.
The symptomatology of this lesion may include drawing pains in the lower abdomen, giving back, separation from the genital tract, an increase in body temperature. In the complex treatment of infectious inflammation of the appendages, Nolycin may be prescribed, the indications of which include this disease. In this case, before the start of therapy, especially when the process is being chronized, it is desirable to carry out bapses and determine the type of pathogen.
Nolycin - how to take?
Preparation Nolitsin method of use is simple - the tablet should be swallowed whole, without chewing and not rassasyvaya. It is important to consume large amounts of water during admission, which contributes to better dissolution and absorption of the drug. Slow down and make the assimilation of the medicament incomplete food, so drink the tablet should be an hour before or a couple of hours after a meal.
How to take Nolitsin with cystitis, urethritis, cervicitis and other ailments will be recommended by the attending physician, based on the characteristics of the pathological process. Nolitsin, the dosage of which in the treatment of a day is a maximum of 800 mg (2 tablets in two divided doses), for prophylactic purposes, one-half tablets per day can be taken for a long course (up to 3 years). If the kidney function is impaired, the dose is adjusted.
Nolycin - side effects
Along with the effective suppression of infectious processes in various organs and systems, the drug in question is capable of adversely affecting the body and even provoking certain pathologies. Most of all, the digestive tract and urinary system are subjected to the loading and aggressive influence of the active ingredient. Let's list the side effects of Nolicin in most cases:
- nausea;
- vomiting;
- bitter taste in the mouth;
- jaundice;
- poor appetite;
- diarrhea;
- disturbances of urination;
- excretion of protein in the urine;
- discharge of blood from the urethra;
- lowering blood pressure;
- heart rhythm disorder;
- inflammation of the vascular walls;
- headache;
- sleep disorders;
- depressive state;
- itching;
- a rash on the body;
- swelling;
- soreness of the joints;
- thrush;
- increased fatigue;
- epileptic seizures, etc.
Nolitsin - contraindications
The drug Nolitsin use is limited, as well as other antibiotic drugs. Thus, the drug is not used in pediatric practice and can not be recommended for people who are intolerant of one or more components of the composition of tablets. Nolitsin, the testimony to the application of which is extensive, has other limitations for reception:
- deficiency of glucose-6-phosphate dehydrogenase;
- the presence in the anamnesis of ruptures of tendons connected with the reception of quinoline derivatives;
- period of gestation;
- lactation period.
With caution, under strict control, the drug is used by patients with intolerance to acetylsalicylic acid, suffering from atherosclerosis of cerebral vessels, epilepsy, liver and kidney disorders. In addition, when appointing the pills under consideration, the attending physician should take into account what preparations the patient takes in parallel.
Nolitsin in pregnancy
Nolicin is not recommended for pregnant women. its influence on the fetus has been studied insufficiently, and the risk of the negative influence of norfloxacin on the course of pregnancy is great. However, in extreme cases, the drug is still prescribed to women in the situation. These are difficult situations, when the development of infection threatens the life of the future mother.
Nolycin with breastfeeding
Medication Nolitsin, the indications for the use of which are discussed in detail above, during the period of breastfeeding the baby is forbidden to drink. The antibiotic easily penetrates into the mother's milk and can be contained in it in a high concentration, harmful to the health of the baby. Therefore, during the period of treatment should stop feeding, and, in order to maintain lactation, it is recommended to express on a regular basis.
Nolycin and alcohol compatibility
Nolitsin, indications for the application of which include common infectious pathologies, should be taken in consideration of the rules for taking antibiotics. As you know, antibiotic therapy excludes the simultaneous use of alcoholic beverages because of the unpredictability of negative reactions from the body. The drug in question is not an exception, therefore Nolitsin and alcohol are incompatible concepts.