Creatinine is the norm

Creatinine is a substance of the body's vital activity, obtained as a result of a creatine phosphate reaction (muscle metabolism). The excretion of creatinine occurs during urination, so the urine creatinine rate is an important indicator of kidney function. The kidneys of a healthy person, aged 20-30 years, can filter creatinine into the urine from the blood in a volume of approximately 125 ml per minute. This indicator is called the creatinine clearance and can normally be from 80 to 150 ml / m.

Creatinine

Since this molecular structure depends on the individual volume of muscle tissue, the creatinine level in the blood is different for women and men. In males, due to the structure, the creatinine norm in the blood test is almost twice as high. In addition, the muscle mass of the average person, changes not quickly, so this indicator is always a value. For an adult male, the creatinine rate ranges from 74.0 to 110.0 μmol / L. Depending on age, this level can fluctuate either upwards (for young men or actively engaged in sports), and downwards (older men who have obesity or muscle diseases).

For the average woman of average age, the level of creatinine in the blood ranges from 44.0 to 80.0 μmol / l. His fluctuations can cause protein diets (increase), as well as the first two trimester of pregnancy (decrease).

In the biochemical analysis of blood in children under one year, creatinine is the norm in the range of 45.0 to 100, 0 μmol / L. After reaching the age of one year, this indicator begins to decline. And at the age of 14 years the rate of creatinine of the child is 27 - 62 μmol / l.

In addition to the factors already mentioned, fluctuations in the creatinine index can be noted with vegetarian food, starvation, and dehydration. Extensive burn lesions of the skin, intestinal obstruction , necrosis of the muscles as a result of prolonged pressure also change the creatinine index.

Also, other factors can influence this level of this structure:

In addition to creatinine in the blood, its quantity in the urine also has its own norms. For women, the creatinine in urine is 0.8 to 1.8 grams or 7.1 to 15.9 mmol. The male index is higher and lies in the range of 1.0 to 2.0 grams (8.8 to 17.7 mmol).

How can I test for creatinine?

To obtain the most complete information on the content of creatinine, and accordingly the quality of kidney function, blood and urine tests are usually prescribed. To obtain reliable information as a result of the analysis, you should prepare. To do this, for 36-48 hours before blood sampling:

  1. Stop active physical activities.
  2. Reduce the consumption of protein foods (not more than 200 grams).
  3. After consulting with a doctor, suspend the use of medications containing cortisol , corticotropin, thyroxine.

The blood test is done on an empty stomach, i.е. From the time of the last meal to the collection of blood should pass at least 9 hours.

To study the level of creatinine and its clearance in the urine, you need to collect its daily rate on its own. For this, most often, a sterile plastic container with a volume of 4-5 liters is used. all urine must be in the same container. The rules for collecting urine:

  1. Begin collecting the material should be from the second emptying of the bladder after awakening.
  2. Portions are used completely.
  3. To store the container with analysis, use a cool place, for example, a refrigerator.
  4. During the day, an abundant drink is recommended (it is desirable to exclude teas, coffee, juices).
  5. The last portion of urine should be the next morning, immediately after awakening.
  6. When emptying the bladder, try to keep it clean, there should not be any foreign inclusions, such as feces, hair, etc.

In the case of menstruation, urine analysis should be postponed to another day.