The way it is used depends on its speed and the number of possible side effects. Prednisolone in tablets has a cumulative effect and is shown with prolonged therapy, while Prednisolone in ampoules is used in situations where any delay is dangerous, it begins to act after 15-20 minutes with intramuscular injection and for 3-5 minutes with intravenous injections .
Who is shown the drug Prednisolone in ampoules?
The release form of Prednisolone in ampoules does not imply the use of the drug by people without medical training. This very serious medicine can only be used as directed by a doctor. At the heart of the solution for injection is a synthetic analogue of the adrenal hormone cortisone and hydrocortisone, which is several times higher than their degree of activity. The prescription for Prednisolone in ampoules can be obtained only if urgently needed. These are diseases such as:
- collagenoses of different severity;
- connective tissue and vascular diseases;
- autoimmune diseases ;
- lupus;
- vasculitis;
- myocarditis;
- toxic poisoning, anaphylactic shock;
- fever of rheumatic origin;
- acute insufficiency of the adrenal cortex;
- Hodgkin's disease, Addison's disease;
- leukemia and others.
However, Prednisolone and Prednisolone Nycomed in ampoules should be used only if a complete history is collected and studied, or delay in the use of the drug is a threat to life. The combination of therapy with prednisolone and other medications often causes complications of varying severity. Diabetics have a diabetic coma, and patients who take salicylates and anticoagulants increase bleeding. Do not use Prednisolone during pregnancy protection with oral contraceptives, pregnant and lactating women. With barbiturates, anticonvulsants and diuretics, their effect may be significantly reduced.
Contraindications for use
Categorically contraindicated Prednisolone in ampoules when:
- severe form of hypertension;
- infectious diseases without the use of antibiotics;
- nephritis, kidney failure;
- ulcer of the stomach and duodenum;
- endocarditis;
- sciatica;
- insufficient blood circulation;
- tuberculosis;
- syphilis.
Dosage of Prednisolone in ampoules
This drug is a clear, yellowish, odorless liquid. In one ampoule is usually 1 ml of prednisolone, which is 30 mg of active ingredient. There is also packing with a large volume, if necessary, simultaneously enter a significant amount of funds.
The usual dosage is 10-30 mg intramuscularly, for more accurate calculations, an individual approach is necessary.
Intravenously Prednisolone in ampoules is administered only in urgent cases. Adults - 30-90 mg, in rare situations, the dose reaches 200 mg.
When the drug is injected into the body of the joint, 30-60 mg for large joints, 10-20 mg for joints of the middle
For children, the dosage is calculated as 1-3 mg per 1 kg of weight, depending on the age. Use for treatment of babies up to 3 months is not allowed. Also, a reduced dosage is used in the treatment of elderly people, while elderly over 70 years of age are extremely undesirable.
After the acute phase of the disease is stopped, Prednisolone in ampoules is replaced with a similar agent in tablets. The course of treatment with the drug should not exceed 14 days.
This medicine is metabolized in the liver and excreted and the body gradually. For the most part - within 3 hours after taking. About 20% of the drug leaves the body with urine in an unchanged state.