Glucocorticosteroid is a substance of natural or synthetic origin. It refers to the subclass of hormones in the adrenal cortex. Preparations from the group of glucocorticosteroids have an immunosuppressive effect and increase the formation of glucose in the liver, so they are often used in the treatment of various diseases.
How does glucocorticosteroids affect the body?
The main biological significance of glucocorticosteroids is to significantly increase the body's resistance to stress. These medicines are even used to suppress the aggression of the immune system, which is directed at one's own organism. This condition occurs when organ transplants, malignant tumors and autoimmune diseases. In addition, glucocorticosteroids affect the mineral, water, carbohydrate and protein metabolism. They are also used as anti-inflammatory, antitoxic and desensitizing agents. In the treatment can be used such forms of drugs:
- intranasal;
- parenteral;
- inhaled glucocorticosteroids.
These medicines have the ability to raise blood pressure. It is realized due to a significant increase in the release of adrenaline, as well as the narrowing of the lumen of blood vessels. This allows using glucocorticosteroids to deal with shock states in particularly critical situations.
Names of drugs from the group of glucocorticosteroids
There are quite a few preparations from the group of glucocorticosteroids, and the names of some of them are familiar to a large number of people, because they are used to treat common diseases. The most popular tools of this kind:
- Belogen - cream or ointment for external use. It is used for eczema , diffuse neurodermatitis, atopic and other dermatitis.
- Sherisolone - tablets that are related to systemic glucocorticosteroids. Used to treat scleroderma , nodular periarteritis, rheumatoid arthritis.
- Cortonisol is an aerosol used in colitis, Crohn's disease, proctitis and ulcerative colitis.
- Solu Medrol is a lyophilizate for the preparation of a solution or a liquid suspension for injection. It is used for burn and operating shock, acute allergic reactions.
Each drug from the list of glucocorticosteroids has contraindications. Virtually any of them should not be used for diabetes, Cushing's disease, thromboembolism and severe renal failure. It is not necessary to carry out treatment with glucocorticosteroids during the active form of tuberculosis and syphilis.